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Home PageAll MoleculesALPI
ALPI
ALPI Overview
| English Name | Intestinal alkaline phosphatase | Approved Drugs | 0 |
| Drugs in Clinical Trials | 1 | Target Synonym | IAP，Intestinal-type alkaline phosphatase，Intestinal-Type Alkaline Phosphatase，Alkaline Phosphomonoesterase，Glycerophosphatase，Kasahara Isozyme |
| Highest Development Stage | Phase 1 Clinical | ||
| English Name | Intestinal alkaline phosphatase |
| Target Synonym | IAP，Intestinal-type alkaline phosphatase，Intestinal-Type Alkaline Phosphatase，Alkaline Phosphomonoesterase，Glycerophosphatase，Kasahara Isozyme |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 1 |
| Highest Development Stage | Phase 1 Clinical |
ALPI Product List
- Product Category
Protein (4)
- Product Status
Launched (4)
- Species
Human (2)Cynomolgus (1)Mouse (1)
- Tag
His Tag (3)His Tag & Avi Tag (1)
- Conjugate
Unconjugated (3)Biotin-labeled (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
ALI-H52H3 |  Human | HEK293 | Human ALPI Protein, His Tag (active enzyme, MALS verified) |  |  |  |
ALI-H82E3 | Human | HEK293 | Biotinylated Human ALPI Protein, His,Avitag™ (active enzyme, MALS verified) |  | | |
ALI-M52H4 |  Mouse | HEK293 | Mouse ALPI Protein, His Tag (active enzyme, MALS verified) |  | | |
ALI-C52H3 |  Cynomolgus | HEK293 | Cynomolgus ALPI Protein, His Tag (MALS verified) |  | | |
Total: 4
- 1
ALPI Background
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut.
ALPI Synonyms
IAP
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Oral alkaline phosphatase (Synthetic Biologics) | SYN-020 | Phase 1 Clinical | Theriva Biologics Inc, Massachusetts General Hospital | Enteritis; Inflammatory Bowel Diseases; Metabolic Syndrome; Celiac Disease | Details |
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