DLL4

DLL4 Informations sur la molécule

Nom anglais	Delta-like protein 4	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	3	Alias de la cible	Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog
Phase de R&D la plus avancée	Phase 3 Clinical

Nom anglais	Delta-like protein 4
Alias de la cible	Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	3
Phase de R&D la plus avancée	Phase 3 Clinical

DLL4 Liste de produits

Attribut
Protein (10)Cell Grade Beads (4)Kits (2)
Bibliothèque de produits
En ligne (16)
Espèces
Human (13)- (3)
Étiquette
Fc Tag (6)His Tag (1)His Tag & Avi Tag (2)- (6)Fc Tag & Avi Tag (1)
Marqueur
Unconjugated (7)Biotin-labeled (3)- (6)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT DL4-H5255	Human	HEK293	Human DLL4 Protein, Fc Tag, premium grade (Flagship)	Ajouter au panier
HOT DL4-H5259	Human	HEK293	Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)	Ajouter au panier
HOT DL4-H82E6	Human	HEK293	Biotinylated Human DLL4 Protein, His,Avitag™, premium grade	Ajouter au panier
HOT GMP-DL4H23	Human	HEK293	GMP Biotinylated Human DLL4 Protein, His,Avitag™	Ajouter au panier
HOT GMP-DL4H27	Human	HEK293	GMP Human DLL4 Protein, Fc Tag (Flagship)	Ajouter au panier
HOT GMP-DL4H28	Human	HEK293	GMP Human DLL4 Protein, Fc Tag	Ajouter au panier
HOT MBS-C013	Human	-	ActiveMax® Human DLL4 μBeads, premium grade (for cells)	Ajouter au panier
DL4-H5227	Human	HEK293	Human DLL4 Protein, His Tag, low Endotoxin (MALS verified)	Ajouter au panier
DL4-H5256	Human	HEK293	Human DLL4 Protein, Fc Tag, Research Grade (Flagship)	Ajouter au panier
DL4-H82F7	Human	HEK293	Biotinylated Human DLL4 Protein, Fc,Avitag™, premium grade	Ajouter au panier

Quantité totale16

DLL4Contexte de la molécule

Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.

DLL4Alias de la molécule

DLL4,Delta4

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Tovecimig	ES-104; NOV-1501; CTX-009; HD-B001A; HDB001A; TR-009; ABL001; ABL-001	Phase 3 Clinical	Abl Bio Inc	Biliary Tract Neoplasms; Solid tumours; Rectal Neoplasms; Colonic Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Bile Duct Neoplasms; Ampullary Carcinoma; Gallbladder Neoplasms	Details
Navicixizumab	OMP-305B83	Phase 3 Clinical	Oncomed Pharmaceuticals Inc	Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Triple Negative Breast Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms	Details
Dilpacimab	ABT-165; DVD-Ig ABT-165	Phase 1 Clinical	Abbvie Inc	Solid tumours; Neoplasms	Details

Avis sur les produits

Z***a2022-07-06
1Mettre un like
Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
This product was extremely useful for our T cell work. The vial it came in was easy to use (sometimes you'd be surprised how obtuse the packaging of a compound can be by certain companies) and has not lead to any issues with our research in many months. The only obstacle we have ever faced with adherent cells was as a result of our flat bottom plates being too old (and thus the coating wore off). So this product was more stable and consistent than the plates we put them on!