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B7-H6

B7-H6 Liste de produits

  • Attribut

    Protein (4)

  • Bibliothèque de produits

    En ligne (6)

  • Espèces

    Human (3)Cynomolgus (1)

  • Étiquette

    His Tag & Avi Tag (1)His Tag (2)Fc Tag & Avi Tag (1)

  • Marqueur

    Biotin-labeled (2)Unconjugated (2)

B7-H6Contexte de la molécule

The B7 family of genes is essential in the regulation of the adaptive immune system. one of which is the recently discovered B7H6. Humans and rats have a single B7H6 gene; however, many B7H6 genes were detected in a single large cluster in the Xenopus genome. Chimeric antigen receptor (CAR) T-cell therapies have demonstrated durable and potentially curative therapeutic efficacy against B-cell leukemia in clinical trials. In this study, B7H6, a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.

Avis sur les produits

  • W***I2025-11-07
    0Mettre un like
    Human MICA target recombinant protein has always been from ACROBiosystems. The protein quality of each batch is very stable, and batch-to-batch differences are extremely small, which is very beneficial for the entire project development. Must support ACRO.
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