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FGF acidic

FGF acidic Informations sur la molécule

Nom anglaisFibroblast growth factor 1Nombre de médicaments commercialisés0
Nombre de médicaments cliniques2Alias de la cibleFibroblast Growth Factor 1 (Acidic),HBGF1,Acidic fibroblast growth factor,Heparin-binding growth factor 1,HBGF-1,Endothelial cell growth factor,FGF1,Fibroblast Growth Factor 1,Endothelial Cell Growth Factor, Alpha,Endothelial Cell Growth Factor, Beta,FGF-1,AFGF,FGFA,ECGF,Beta-Endothelial Cell Growth Factor,ECGF-Beta,FGF-Alpha,GLIO703,ECGFA,ECGFB
Phase de R&D la plus avancéePhase 3 Clinical
Nom anglaisFibroblast growth factor 1
Alias de la cibleFibroblast Growth Factor 1 (Acidic),HBGF1,Acidic fibroblast growth factor,Heparin-binding growth factor 1,HBGF-1,Endothelial cell growth factor,FGF1,Fibroblast Growth Factor 1,Endothelial Cell Growth Factor, Alpha,Endothelial Cell Growth Factor, Beta,FGF-1,AFGF,FGFA,ECGF,Beta-Endothelial Cell Growth Factor,ECGF-Beta,FGF-Alpha,GLIO703,ECGFA,ECGFB
Nombre de médicaments commercialisés0
Nombre de médicaments cliniques2
Phase de R&D la plus avancéePhase 3 Clinical

FGF acidic Liste de produits

  • Attribut

    Protein (1)

  • Bibliothèque de produits

    En ligne (1)

  • Espèces

    Human (1)

  • Étiquette

    Tag Free (1)

  • Marqueur

    Unconjugated (1)

Numéro de produitEspècesSystème d'expressionDescription du produitStructure protéiquePuretéCaractéristiquesPré-commande/Commande
AFF-H4116
Human
E. coli
Human FGF acidic Protein, Tag Free
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FGF acidicContexte de la molécule

Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.

FGF acidicAlias de la molécule

FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1

Informations sur les médicaments cliniques

Nom anglaisCode de recherchePhase de R&DEntrepriseIndicationEssai clinique
Muparfostat sodiumPI-88Phase 3 ClinicalAustralian National UniversityLiver Neoplasms; Skin Melanoma; Solid tumours; Neoplasms; Prostatic Neoplasms; Lung Neoplasms; Carcinoma, Hepatocellular; Melanoma; Carcinoma, Non-Small-Cell Lung
Details
TTHX-1114TTHX-1114; NM-141; NM141; TTHX1114Phase 2 ClinicalFlorida State UniversityCorneal Diseases; Corneal Dystrophies, Hereditary; Vascular Diseases; Fuchs' Endothelial Dystrophy
Details

Avis sur les produits

  • W***G2025-11-07
    0Mettre un like
    Both antibodies and proteins are great, the instructions are also detailed. Reasonable price. Hope to progress together.
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