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Monoclonal Anti-Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Antibody, Human IgG1 (8A1) (MALS verified)

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Numéro de produit/spécification
Prix
Qté
HA1-M694-100ug
$360.00
HA1-M694-1mg
$2380.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Source

    Monoclonal Anti-Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Antibody, Human IgG1 (8A1) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

  • Clone

    8A1

  • Species

    Mouse

  • Isotype

    Human IgG1 | Human Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Virus

  • Immunogen

    Recombinant Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Protein is expressed from human 293 cells

  • Specificity

    This product is a specific antibody specifically reacts with Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] Hemagglutinin (HA) and HA1.

  • Application

    Application
    Recommended Usage
    ELISA
    0.006-8 ng/mL
  • Purity

    90% as determined by SDS-PAGE.

    95% as determined by SEC-MALS.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

    For best performance, we strongly recommend following the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Cross Verification

    This product No cross-reactivity in ELISA with

    Influenza A [A/Shanghai/2/2013(H7N9)] HA, Fc Tag (Cat. No. HA9-V5253).

    Influenza A [A/Darwin/9/2021 (H3N2)] HA Protein, His Tag (Cat. No. HA2-V52H6).

    Influenza A [A/Hong Kong/483/97 (H5N1)] HA, His Tag (Cat. No. HA1-V5229).

    Influenza A [A/Wisconsin/588/2019 (H1N1)] HA, His Tag (Cat. No. HA1-V52H3).

    Influenza A [A/Bangkok/1/1979 (H3N2)] HA, His Tag (Cat. No. HA2-V52H3).

    Influenza A [A/Darwin/6/2021 (H3N2)] HA Protein, His Tag (Cat. No. HA2-V52H5).

    Influenza A [Sydney/5/2021 (H1N1)] HA Protein, His Tag (Cat. No. HA1-V52H4).

    Influenza B [Austria/1359417/2021 (B/Victoria lineage)] Hemagglutinin (HA) Protein, His Tag (Cat. No. HAE-V52H3).

    Influenza B [Phuket/3073/2013 (B/Yamagata lineage)] HA Protein, His Tag (Cat. No. HAE-V52H4).

    Influenza A [A/Victoria/2570/2019] Hemagglutinin (HA) Protein, His Tag (Cat. No. HA1-V52H6).

    Influenza A (A/Shanghai/02/2013(H7N9)) Hemagglutinin (HA) Protein, His Tag (Cat. No. HA9-V52H3).

    Influenza A [Victoria/4897/2022] Hemagglutinin (HA) Protein, His Tag (Cat. No. HA1-V52H8).

    Influenza A (turkey/Germany-MV/R2472/2014(H5N8)) HA Protein, His Tag (Cat. No. HA8-V52H3).

    Influenza A (Guangdong/18SF020(H5N6)) Hemagglutinin (HA) Protein, His Tag (Cat. No. HA6-V52H3).

    Influenza A (Vietnam/1194/2004(H5N1)) Hemagglutinin (HA) Protein, His Tag (Cat. No. HA1-V52H9).

    Influenza A [Wisconsin/67/2022] Hemagglutinin (HA) Protein, His Tag (Cat. No. HA1-V52H7).

    Influenza A Virus (A/District of Columbia/27/2023) HA (H3N2) Protein, His Tag (Cat. No. H32-V52H5).

    Influenza A Virus (A/Croatia/10136RV/2023) HA (H3N2) Protein, His Tag (Cat. No. H32-V52H4).

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Affichage des données

  • SDS-PAGE

    Hemagglutinin 1/HA 1 (Influenza Virus) SDS-PAGE

    Monoclonal Anti-Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Antibody, Human IgG1 (8A1) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Hemagglutinin 1/HA 1 (Influenza Virus) SEC-MALS

    The purity of Monoclonal Anti-Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Antibody, Human IgG1 (8A1) (Cat. No. HA1-M694) is more than 95% and the molecular weight of this protein is around 140-165 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Hemagglutinin 1/HA 1 (Influenza Virus) ELISA

    Immobilized Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Protein, His Tag (Cat. No. HA1-V52H5) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Antibody, Human IgG1 (8A1) (Cat. No. HA1-M694) with a linear range of 0.006-0.8 ng/mL (QC tested).

    Protocol
  •  Hemagglutinin 1/HA 1 (Influenza Virus) ELISA

    Immobilized Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] Hemagglutinin (HA) Protein, His Tag (Cat. No. HA2-V52H7) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Antibody, Human IgG1 (8A1) (Cat. No. HA1-M694) with a linear range of 0.005-0.8 ng/mL (QC tested).

    Protocol
  • Bioactivity-SPR

     Hemagglutinin 1/HA 1 (Influenza Virus) SPR

    Monoclonal Anti-Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Antibody, Human IgG1 (8A1) (Cat. No. HA1-M694) captured on Protein A Chip can bind Influenza A [A/guinea fowl/Hong Kong/WF10/99(H9N2)] HA1 Protein, His Tag (Cat. No. HA1-V52H5) with an affinity constant of 2.10 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

    Protocol

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Introduction de fond

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. HA molecules are proteolytically cleaved into HA1 and HA2 glycopolypeptides intra- or extracellularly, depending on the structure of the cleavage site.

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  • Informations de base sur le produit
  • Détails du produit
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