Product Details
Synonym
PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
Source
Canine PD-L1, Fc Tag (PD1-C52H3) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - His 238 (Accession # E2RKZ5-1).
Predicted N-terminus: Phe 19
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 51.4 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
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Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Canine PD-L1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.
Bioactivity-BLI

Loaded Canine PD-1, His Tag (Cat. No. PD1-C52H9) on HIS1K Biosensor, can bind Canine PD-L1, Fc Tag (Cat. No. PD1-C52H3) with an affinity constant of 85 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Protocol
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Background
Recent Advances
- English Name:
Programmed death-ligand 1
- Category:
- Approved Drugs:
12 Details
- Drugs in Clinical Trials:
176 Details
- Highest Development Stage:
Approved




















